New Type II Manumycins Produced by Streptomyces nodosus ssp. asukaensis and Their Biosynthesis.
نویسندگان
چکیده
منابع مشابه
New paulomycins produced by Streptomyces paulus.
Paulomycin A2 (C34H46N2O17S), paulomycin C (C32H42N2O17S), paulomycin D (C31H40N2O17S), paulomycin E (C29H36N2O16S) and paulomycin F (C29H38N2O16S) have been isolated from fermentations of Streptomyces paulus strain 273. The structure of these compounds was determined using NMR and mass spectroscopic techniques. The new paulomycins, like paulomycins A and B (J. Antibiotics 35: 285-294, 1982) ar...
متن کاملA new antibiotic,, asukamycin, produced by Streptomyces.
Asukamycin, a new antibiotic, has been isolated from the culture broth of a streptomycete designated as Streptomyces nodosus subsp. asukaensis. The antibiotic inhibits the growth of Gram-positive bacteria including Nocardia asteroides. The empirical formula of antibiotic asukamycin has been proposed as C29H22N2O9 (M.W. 542). An acute toxicity of the antibiotic in mice is LD50 48.5 mg/kg by intr...
متن کاملEpostatin, new inhibitor of dipeptidyl peptidase II, produced by streptomyces sp. MJ995-OF5 II. Structure elucidation.
During the course of screening fermentation broths for new inhibitors of dipeptidyl peptidase II (EC 3.4.14.2), we discovered epostatin (C23H33N3O5) from Streptomyces sp. MJ995-OF5. The taxonomy of producing strain, fermentation, isolation, physico-chemical properties and biological properties have been described in the preceding paper1). Herein we report on the structure determination of epost...
متن کاملAntibiotics produced by Streptomyces.
Streptomyces is a genus of Gram-positive bacteria that grows in various environments, and its shape resembles filamentous fungi. The morphological differentiation of Streptomyces involves the formation of a layer of hyphae that can differentiate into a chain of spores. The most interesting property of Streptomyces is the ability to produce bioactive secondary metabolites, such as antifungals, a...
متن کاملCV-1, a new antibiotic produced by a strain of Streptomyces sp. II. structure determination.
The structure of a new antibiotic, CV-1 was determined to be 1,2-diamino-1,2-N,N'-carbonyl-1,2-dideoxy-alpha-D-glucose hydrate by spectral and chemical studies. CV-1 possessed a unique open ring hemiaminal structure. CV-1 synthesized from N-carbamoyl-D-glucosamine was identical to material isolated from fermentation.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 2001
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.54.340